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Notch4 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN311127BN
Notch4 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR223369 Notch4 (Myc-DDK-tagged) - Mouse Notch gene homolog 4 (Drosophila) (Notch4)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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$265.00

Other products for "Notch4 or NM_010929"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Notch4
Locus ID 18132
Components

KN311127G1, Notch4 gRNA vector 1 in pCas-Guide CRISPR vector

KN311127G2, Notch4 gRNA vector 2 in pCas-Guide CRISPR vector

KN311127BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_010929
UniProt ID P31695
Synonyms Int-3; Int3; N4
Summary Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May regulate branching morphogenesis in the developing vascular system.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA202939 Notch4 CRISPRa kit - CRISPR gene activation of mouse notch 4 1 kit
$1,657.00
KN311127 Notch4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN311127LP Notch4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN311127RB Notch4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN511127 Notch4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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