Mouse Notch4 activation kit by CRISPRa

SKU
GA202939
Notch4 CRISPRa kit - CRISPR gene activation of mouse notch 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Notch4
Locus ID 18132
Components

GA202939G1, Notch4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202939G2, Notch4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202939G3, Notch4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_010929
UniProt ID P31695
Synonyms Int-3; Int3; N4
Summary Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May regulate branching morphogenesis in the developing vascular system.UniProtKB/Swiss-Prot Function
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Other Versions
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KN311127 Notch4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN311127BN Notch4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN311127LP Notch4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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