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Cgas Mouse Gene Knockout Kit (CRISPR)

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SKU
KN309828RB
Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR213022 MB21D1 (Myc-DDK-tagged) - Mouse Mab-21 domain containing 1 (Mb21d1)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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$265.00

Other products for "Cgas or BC052196"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Cgas
Locus ID 214763
Components

KN309828G1, Cgas gRNA vector 1 in pCas-Guide CRISPR vector

KN309828G2, Cgas gRNA vector 2 in pCas-Guide CRISPR vector

KN309828RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_173386, NR_125721
UniProt ID Q8C6L5
Synonyms cGAS; E330016A19Rik
Summary The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014
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Documents
Resources
Other Versions
SKU Description Size Price
GA213232 Cgas CRISPRa kit - CRISPR gene activation of mouse cyclic GMP-AMP synthase 1 kit
$1,657.00
KN309828 Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309828BN Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309828LP Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN509828 Mb21d1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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