Mouse Cgas activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Cgas |
| Locus ID | 214763 |
| Components |
GA213232G1, Cgas gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213232G2, Cgas gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213232G3, Cgas gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_173386, NR_125721 |
| UniProt ID | Q8C6L5 |
| Synonyms | cGAS; E330016A19Rik |
| Summary | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN309828 | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
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| KN309828BN | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN309828LP | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN309828RB | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN509828 | Mb21d1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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