Lox Mouse Gene Knockout Kit (CRISPR)
CAT#: KN309375LP
Lox - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Lox |
Locus ID | 16948 |
Components |
KN309375G1, Lox gRNA vector 1 in pCas-Guide CRISPR vector KN309375G2, Lox gRNA vector 2 in pCas-Guide CRISPR vector KN309375LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001286181, NM_001286182, NM_010728 |
UniProt ID | P28301 |
Synonyms | AI893619; rrg; TSC-160 |
Summary | This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
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KN309375 | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN309375BN | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN309375RB | Lox - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN509375 | Lox - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA202483 | Lox CRISPRa kit - CRISPR gene activation of mouse lysyl oxidase |
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