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Klf15 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN308828BN
Klf15 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR206548 Klf15 (Myc-DDK-tagged) - Mouse Kruppel-like factor 15 (Klf15)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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$265.00

Other products for "Klf15 or BC013486"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Klf15
Locus ID 66277
Components

KN308828G1, Klf15 gRNA vector 1 in pCas-Guide CRISPR vector

KN308828G2, Klf15 gRNA vector 2 in pCas-Guide CRISPR vector

KN308828BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_023184, NM_001355668
UniProt ID Q9EPW2
Synonyms 1810013I09Rik; AV048136; AW494632; CKLF; KKLF
Summary Transcriptional regulator that binds to the GA element of the CLCNKA promoter (By similarity). Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart. Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. Is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A, GATA4 and MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation (By similarity). Involved in podocyte differentiation.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
GA206684 Klf15 CRISPRa kit - CRISPR gene activation of mouse Kruppel-like factor 15 1 kit
$1,657.00
KN308828 Klf15 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN308828LP Klf15 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN308828RB Klf15 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN508828 Klf15 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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