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Il6 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN308293BN
Il6 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Il6 or BC132458"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Il6
Locus ID 16193
Components

KN308293G1, Il6 gRNA vector 1 in pCas-Guide CRISPR vector

KN308293G2, Il6 gRNA vector 2 in pCas-Guide CRISPR vector

KN308293BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_031168
UniProt ID P08505
Synonyms Il-6
Summary This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
GA202149 Il6 CRISPRa kit - CRISPR gene activation of mouse interleukin 6 1 kit
$1,657.00
KN308293 Il6 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN308293LP Il6 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN308293RB Il6 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN508293 Il6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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