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Folr1 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN306057LP
Folr1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Folr1 or NM_001252552"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Folr1
Locus ID 14275
Components

KN306057G1, Folr1 gRNA vector 1 in pCas-Guide CRISPR vector

KN306057G2, Folr1 gRNA vector 2 in pCas-Guide CRISPR vector

KN306057LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001252552, NM_001252553, NM_001252554, NM_008034
UniProt ID P35846
Synonyms FBP1; Folbp-1; Folbp1
Summary Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA201461 Folr1 CRISPRa kit - CRISPR gene activation of mouse folate receptor 1 (adult) 1 kit
$1,657.00
KN306057 Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN306057BN Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN306057RB Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN506057 Folr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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