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Mouse Folr1 activation kit by CRISPRa

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SKU
GA201461
Folr1 CRISPRa kit - CRISPR gene activation of mouse folate receptor 1 (adult)
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Folr1
Locus ID 14275
Components

GA201461G1, Folr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201461G2, Folr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201461G3, Folr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001252552, NM_001252553, NM_001252554, NM_008034
UniProt ID P35846
Synonyms FBP1; Folbp-1; Folbp1
Summary Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN306057 Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN306057BN Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN306057LP Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN306057RB Folr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN506057 Folr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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