Dusp1 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN304862LP

Dusp1 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: Dusp1
• Locus ID: 19252
• Components:

  KN304862G1, Dusp1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN304862G2, Dusp1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN304862LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_013642
• UniProt ID: P28563
• Synonyms: 3CH134; erp; mkp-1; MKP1; Ptpn16; U19515
• Summary: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.[UniProtKB/Swiss-Prot Function]