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Ddr1 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN304371RB
Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR223468 Ddr1 (Myc-DDK-tagged) - Mouse discoidin domain receptor family, member 1 (Ddr1), transcript variant 1
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Other products for "Ddr1 or BC065998"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Ddr1
Locus ID 12305
Components

KN304371G1, Ddr1 gRNA vector 1 in pCas-Guide CRISPR vector

KN304371G2, Ddr1 gRNA vector 2 in pCas-Guide CRISPR vector

KN304371RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001198831, NM_001198833, NM_007584, NM_172962
UniProt ID Q03146
Synonyms 6030432F18; AI323681; Cak; CD167a; Nep; PTK3A
Summary Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA200491 Ddr1 CRISPRa kit - CRISPR gene activation of mouse discoidin domain receptor family, member 1 1 kit
$1,657.00
KN304371 Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304371BN Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304371LP Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504371 Ddr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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