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Mouse Ddr1 activation kit by CRISPRa

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SKU
GA200491
Ddr1 CRISPRa kit - CRISPR gene activation of mouse discoidin domain receptor family, member 1
  $1,657.00
4 Weeks*

Other products for "Ddr1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ddr1
Locus ID 12305
Components

GA200491G1, Ddr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200491G2, Ddr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200491G3, Ddr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001198831, NM_001198833, NM_007584, NM_172962
UniProt ID Q03146
Synonyms 6030432F18; AI323681; Cak; CD167a; Nep; PTK3A
Summary Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN304371 Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304371BN Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304371LP Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304371RB Ddr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504371 Ddr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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