Cxxc5 Mouse Gene Knockout Kit (CRISPR)

SKU
KN304060LP
Cxxc5 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Cxxc5
Locus ID 67393
Components

KN304060G1, Cxxc5 gRNA vector 1 in pCas-Guide CRISPR vector

KN304060G2, Cxxc5 gRNA vector 2 in pCas-Guide CRISPR vector

KN304060LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_133687, NM_001357458, NM_001357459
UniProt ID Q91WA4
Synonyms 4930415K17Rik
Summary May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis (By similarity). Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA207305 Cxxc5 CRISPRa kit - CRISPR gene activation of mouse CXXC finger 5 1 kit
$1,657.00
KN304060 Cxxc5 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304060BN Cxxc5 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304060RB Cxxc5 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504060 Cxxc5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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