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Ctsb Mouse Gene Knockout Kit (CRISPR)

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SKU
KN303984LP
Ctsb - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "Ctsb or BC006656"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Ctsb
Locus ID 13030
Components

KN303984G1, Ctsb gRNA vector 1 in pCas-Guide CRISPR vector

KN303984G2, Ctsb gRNA vector 2 in pCas-Guide CRISPR vector

KN303984LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_007798
UniProt ID P10605
Synonyms CB
Summary This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. provided by RefSeq, Aug 2015
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Other Versions
SKU Description Size Price
GA200946 Ctsb CRISPRa kit - CRISPR gene activation of mouse cathepsin B 1 kit
$1,657.00
KN303984 Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303984BN Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303984RB Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN503984 Ctsb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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