Mouse Ctsb activation kit by CRISPRa

SKU
GA200946
Ctsb CRISPRa kit - CRISPR gene activation of mouse cathepsin B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ctsb
Locus ID 13030
Components

GA200946G1, Ctsb gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200946G2, Ctsb gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200946G3, Ctsb gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_007798
UniProt ID P10605
Synonyms CB
Summary This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. provided by RefSeq, Aug 2015
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Other Versions
SKU Description Size Price
KN303984 Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303984BN Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303984LP Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303984RB Ctsb - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN503984 Ctsb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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