Cdk5rap2 Mouse Gene Knockout Kit (CRISPR)

SKU
KN303046LP
Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Cdk5rap2
Locus ID 214444
Components

KN303046G1, Cdk5rap2 gRNA vector 1 in pCas-Guide CRISPR vector

KN303046G2, Cdk5rap2 gRNA vector 2 in pCas-Guide CRISPR vector

KN303046LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001313762, NM_145990
UniProt ID Q8K389
Synonyms 2900018K03Rik; an; mKIAA1633
Summary Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion (PubMed:20627074). Involved in regulation of mitotic spindle orientation (PubMed:20460369). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Required for the recruitment of AKAP9 to centrosomes (By similarity). Plays a role in neurogenesis (PubMed:20471352). Contrary to higher mammalian orthologs, including human, chimpanzee, bovine and dog, does not interact with EB1/MAPRE1, therefore its function in the regulation of microtubule dynamics is unclear (PubMed:19553473).UniProtKB/Swiss-Prot Function
Shipping Ambient
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA213212 Cdk5rap2 CRISPRa kit - CRISPR gene activation of mouse CDK5 regulatory subunit associated protein 2 1 kit
$1,657.00
KN303046 Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303046BN Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303046RB Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN503046 Cdk5rap2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products