Mouse Cdk5rap2 activation kit by CRISPRa

SKU
GA213212
Cdk5rap2 CRISPRa kit - CRISPR gene activation of mouse CDK5 regulatory subunit associated protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cdk5rap2
Locus ID 214444
Components

GA213212G1, Cdk5rap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213212G2, Cdk5rap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213212G3, Cdk5rap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001313762, NM_145990
UniProt ID Q8K389
Synonyms 2900018K03Rik; an; mKIAA1633
Summary Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion (PubMed:20627074). Involved in regulation of mitotic spindle orientation (PubMed:20460369). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Required for the recruitment of AKAP9 to centrosomes (By similarity). Plays a role in neurogenesis (PubMed:20471352). Contrary to higher mammalian orthologs, including human, chimpanzee, bovine and dog, does not interact with EB1/MAPRE1, therefore its function in the regulation of microtubule dynamics is unclear (PubMed:19553473).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN303046 Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN303046BN Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303046LP Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN303046RB Cdk5rap2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN503046 Cdk5rap2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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