Ccl2 Mouse Gene Knockout Kit (CRISPR)

SKU
KN302782RB
Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Ccl2
Locus ID 20296
Components

KN302782G1, Ccl2 gRNA vector 1 in pCas-Guide CRISPR vector

KN302782G2, Ccl2 gRNA vector 2 in pCas-Guide CRISPR vector

KN302782RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_011333
UniProt ID P10148
Synonyms AI323594; HC11; JE; MCAF; MCP-1; MCP1; Scya2; Sigje; SMC-CF
Summary This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. provided by RefSeq, Sep 2015
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Other Versions
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GA203799 Ccl2 CRISPRa kit - CRISPR gene activation of mouse chemokine (C-C motif) ligand 2 1 kit
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KN302782 Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN302782BN Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN502782 Ccl2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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