C1galt1c1 Mouse Gene Knockout Kit (CRISPR)

SKU KN302341BN

C1galt1c1 - mouse gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: C1galt1c1
• Locus ID: 59048
• Components:

  KN302341G1, C1galt1c1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN302341G2, C1galt1c1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN302341BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_021550
• UniProt ID: Q9JMG2
• Synonyms: 1500002I11Rik; AB030184; C1GalT2; C81205; Cosmc
• Summary: Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) (By similarity).[UniProtKB/Swiss-Prot Function]
• Shipping: Ambient