Mouse C1galt1c1 activation kit by CRISPRa

SKU GA206357

C1galt1c1 CRISPRa kit - CRISPR gene activation of mouse C1GALT1-specific chaperone 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: C1galt1c1
• Locus ID: 59048
• Components:

  GA206357G1, C1galt1c1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206357G2, C1galt1c1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206357G3, C1galt1c1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021550
• UniProt ID: Q9JMG2
• Synonyms: 1500002I11Rik; AB030184; C1GalT2; C81205; Cosmc
• Summary: Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) (By similarity).[UniProtKB/Swiss-Prot Function]