Arntl Mouse Gene Knockout Kit (CRISPR)

SKU
KN301604LP
Arntl - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Arntl
Locus ID 11865
Components

KN301604G1, Arntl gRNA vector 1 in pCas-Guide CRISPR vector

KN301604G2, Arntl gRNA vector 2 in pCas-Guide CRISPR vector

KN301604LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001243048, NM_007489
UniProt ID Q9WTL8
Synonyms Arnt3; bHLHe5; Bmal1; BMAL1b; bmal1b'; MOP3
Summary The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2014
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Other Versions
SKU Description Size Price
GA200284 Arntl CRISPRa kit - CRISPR gene activation of mouse aryl hydrocarbon receptor nuclear translocator-like 1 kit
$1,657.00
KN301604 Arntl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN301604BN Arntl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN301604RB Arntl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN501604 Arntl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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