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IRG1 (ACOD1) Human Gene Knockout Kit (CRISPR)

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SKU
KN232825RB
IRG1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "IRG1 or NM_001258406"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol IRG1
Locus ID 730249
Components

KN232825G1, IRG1 gRNA vector 1 in pCas-Guide CRISPR vector

KN232825G2, IRG1 gRNA vector 2 in pCas-Guide CRISPR vector

KN232825RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001258406
UniProt ID A6NK06
Synonyms CAD
Summary Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA119045 ACOD1 CRISPRa kit - CRISPR gene activation of human aconitate decarboxylase 1 1 kit
$1,657.00
KN232825 ACOD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN232825BN IRG1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN232825LP IRG1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN432825 ACOD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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