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Human IRG1 (ACOD1) activation kit by CRISPRa

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SKU
GA119045
ACOD1 CRISPRa kit - CRISPR gene activation of human aconitate decarboxylase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC232825 ACOD1 (Myc-DDK tagged) - Human aconitate decarboxylase 1 (ACOD1)
10 ug
$289.00 $732.00

Other products for "ACOD1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ACOD1
Locus ID 730249
Components

GA119045G1, IRG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA119045G2, IRG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA119045G3, IRG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001258406
UniProt ID A6NK06
Synonyms CAD
Summary Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN232825 ACOD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN232825BN IRG1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN232825LP IRG1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN232825RB IRG1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN432825 ACOD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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