LRP1B Human Gene Knockout Kit (CRISPR)

SKU KN224195BN

LRP1B - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: LRP1B
• Locus ID: 53353
• Components:

  KN224195G1, LRP1B gRNA vector 1 in pCas-Guide CRISPR vector

  KN224195G2, LRP1B gRNA vector 2 in pCas-Guide CRISPR vector

  KN224195BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_018557
• UniProt ID: Q9NZR2
• Synonyms: LRP-DIT; LRPDIT
• Summary: This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016]
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