BRIP1 Human Gene Knockout Kit (CRISPR)

CAT#: KN224085LP

BRIP1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: BRIP1
• Locus ID: 83990
• Components:

  KN224085G1, BRIP1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN224085G2, BRIP1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN224085LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_032043
• UniProt ID: Q9BX63
• Synonyms: BACH1; FANCJ; OF
• Summary: The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq, Jul 2008]