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DUOX1 Human Gene Knockout Kit (CRISPR)

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SKU
KN223832LP
DUOX1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "DUOX1 or NM_017434"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol DUOX1
Locus ID 53905
Components

KN223832G1, DUOX1 gRNA vector 1 in pCas-Guide CRISPR vector

KN223832G2, DUOX1 gRNA vector 2 in pCas-Guide CRISPR vector

KN223832LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_017434, NM_175940
UniProt ID Q9NRD9
Synonyms LNOX1; NOXEF1; THOX1
Summary The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. provided by RefSeq, Jul 2012
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Documents
Resources
Other Versions
SKU Description Size Price
GA110038 DUOX1 CRISPRa kit - CRISPR gene activation of human dual oxidase 1 1 kit
$1,657.00
KN223832 DUOX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223832BN DUOX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223832RB DUOX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN423832 DUOX1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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