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SIK3 Human Gene Knockout Kit (CRISPR)

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SKU
KN223406BN
SIK3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "SIK3 or NM_001281748"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol SIK3
Locus ID 23387
Components

KN223406G1, SIK3 gRNA vector 1 in pCas-Guide CRISPR vector

KN223406G2, SIK3 gRNA vector 2 in pCas-Guide CRISPR vector

KN223406BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001281748, NM_001281749, NM_025164, NM_001366686, NM_001366687
UniProt ID Q9Y2K2
Synonyms L19; QSK; SIK-3
Summary Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis (PubMed:30232230). Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (Probable). Prevents HDAC4 translocation to the nucleus (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
GA108270 SIK3 CRISPRa kit - CRISPR gene activation of human SIK family kinase 3 1 kit
$1,657.00
KN223406 SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223406LP SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223406RB SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN423406 SIK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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