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Human SIK3 activation kit by CRISPRa

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SKU
GA108270
SIK3 CRISPRa kit - CRISPR gene activation of human SIK family kinase 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC223406 SIK3 (Myc-DDK-tagged)-Human SIK family kinase 3 (SIK3)
10 ug
$1,099.00

Other products for "SIK3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SIK3
Locus ID 23387
Components

GA108270G1, SIK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108270G2, SIK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108270G3, SIK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001281748, NM_001281749, NM_025164, NM_001366686, NM_001366687
UniProt ID Q9Y2K2
Synonyms L19; QSK; SIK-3
Summary Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis (PubMed:30232230). Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (Probable). Prevents HDAC4 translocation to the nucleus (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN223406 SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223406BN SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223406LP SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223406RB SIK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN423406 SIK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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