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EP300 Human Gene Knockout Kit (CRISPR)

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SKU
KN223265BN
EP300 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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RC223265 EP300 (Myc-DDK-tagged)-Human E1A binding protein p300 (EP300)
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Other products for "EP300 or NM_001429"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol EP300
Locus ID 2033
Components

KN223265G1, EP300 gRNA vector 1 in pCas-Guide CRISPR vector

KN223265G2, EP300 gRNA vector 2 in pCas-Guide CRISPR vector

KN223265BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001429, N57495, NM_001362843
UniProt ID Q09472
Synonyms KAT3B; p300; RSTS2
Summary This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA101412 EP300 CRISPRa kit - CRISPR gene activation of human E1A binding protein p300 1 kit
$1,657.00
KN223265 EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223265LP EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223265RB EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN423265 EP300 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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