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Human EP300 activation kit by CRISPRa

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SKU
GA101412
EP300 CRISPRa kit - CRISPR gene activation of human E1A binding protein p300
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA351159 Rabbit Polyclonal Anti-EP300 Antibody
100 ul
$205.00
RC223265 EP300 (Myc-DDK-tagged)-Human E1A binding protein p300 (EP300)
10 ug
$2,988.00

Other products for "EP300"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol EP300
Locus ID 2033
Components

GA101412G1, EP300 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101412G2, EP300 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101412G3, EP300 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001429, N57495, NM_001362843
UniProt ID Q09472
Synonyms KAT3B; p300; RSTS2
Summary This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN223265 EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223265BN EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223265LP EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN223265RB EP300 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN423265 EP300 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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