TNFAIP3 Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | TNFAIP3 |
| Locus ID | 7128 |
| Components |
KN221337G1, TNFAIP3 gRNA vector 1 in pCas-Guide CRISPR vector KN221337G2, TNFAIP3 gRNA vector 2 in pCas-Guide CRISPR vector KN221337LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001270507, NM_001270508, NM_006290 |
| UniProt ID | P21580 |
| Synonyms | A20; AISBL; OTUD7C; TNFA1P2 |
| Summary | This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. provided by RefSeq, Jul 2012 |
| Shipping | Ambient |
Reviews
Documents
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA104922 | TNFAIP3 CRISPRa kit - CRISPR gene activation of human TNF alpha induced protein 3 | 1 kit |
$1,657.00
|
|
| KN221337 | TNFAIP3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN221337BN | TNFAIP3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN221337RB | TNFAIP3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN421337 | TNFAIP3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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