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Factor H (CFH) Human Gene Knockout Kit (CRISPR)

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SKU
KN220707RB
CFH - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Factor H or NM_000186"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Factor H
Locus ID 3075
Components

KN220707G1, Factor H gRNA vector 1 in pCas-Guide CRISPR vector

KN220707G2, Factor H gRNA vector 2 in pCas-Guide CRISPR vector

KN220707RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000186, NM_001014975
UniProt ID P08603
Synonyms AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS
Summary This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Oct 2011
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Other Versions
SKU Description Size Price
GA102097 CFH CRISPRa kit - CRISPR gene activation of human complement factor H 1 kit
$1,657.00
KN220707 CFH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220707BN CFH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220707LP CFH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN420707 CFH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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