Human Factor H (CFH) activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CFH |
| Locus ID | 3075 |
| Components |
GA102097G1, Factor H gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102097G2, Factor H gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102097G3, Factor H gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_000186, NM_001014975 |
| UniProt ID | P08603 |
| Synonyms | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS |
| Summary | This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Oct 2011 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN220707 | CFH - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN220707BN | CFH - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN220707LP | CFH - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN220707RB | CFH - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN420707 | CFH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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