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Neurofibromin (NF1) Human Gene Knockout Kit (CRISPR)

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SKU
KN220378
NF1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC226001L3V Lenti ORF particles, NF1 (Myc-DDK tagged) - Human neurofibromin 1 (NF1), transcript variant 3, 200ul, >10^7 TU/mL
200 ul
$1,102.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "Neurofibromin or NM_000267"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol Neurofibromin
Locus ID 4763
Components

KN220378G1, Neurofibromin gRNA vector 1 in pCas-Guide CRISPR vector

KN220378G2, Neurofibromin gRNA vector 2 in pCas-Guide CRISPR vector

KN220378D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000267, NM_001042492, NM_001128147
UniProt ID P21359
Synonyms NFNS; VRNF; WSS
Summary This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA103178 NF1 CRISPRa kit - CRISPR gene activation of human neurofibromin 1 1 kit
$1,657.00
KN220378BN NF1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220378LP NF1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220378RB NF1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN420378 NF1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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