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RPTP mu (PTPRM) Human Gene Knockout Kit (CRISPR)

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SKU
KN219912LP
PTPRM - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "RPTP mu or NM_001105244"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol RPTP mu
Locus ID 5797
Components

KN219912G1, RPTP mu gRNA vector 1 in pCas-Guide CRISPR vector

KN219912G2, RPTP mu gRNA vector 2 in pCas-Guide CRISPR vector

KN219912LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001105244, NM_002845
UniProt ID P28827
Synonyms hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA103941 PTPRM CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type M 1 kit
$1,657.00
KN219912 PTPRM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219912BN PTPRM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219912RB PTPRM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419912 PTPRM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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