VEGF Receptor 2 (KDR) Human Gene Knockout Kit (CRISPR)

SKU
KN219851LP
KDR - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol VEGF Receptor 2
Locus ID 3791
Components

KN219851G1, VEGF Receptor 2 gRNA vector 1 in pCas-Guide CRISPR vector

KN219851G2, VEGF Receptor 2 gRNA vector 2 in pCas-Guide CRISPR vector

KN219851LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002253
UniProt ID P35968
Synonyms CD309; FLK1; VEGFR; VEGFR2
Summary Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. provided by RefSeq, May 2009
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Other Versions
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GA102564 KDR CRISPRa kit - CRISPR gene activation of human kinase insert domain receptor 1 kit
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KN219851 KDR - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN219851BN KDR - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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