SAP155 (SF3B1) Human Gene Knockout Kit (CRISPR)

SKU
KN219649RB
SF3B1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol SAP155
Locus ID 23451
Components

KN219649G1, SAP155 gRNA vector 1 in pCas-Guide CRISPR vector

KN219649G2, SAP155 gRNA vector 2 in pCas-Guide CRISPR vector

KN219649RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001005526, NM_001308824, NM_012433
UniProt ID O75533
Synonyms Hsh155; MDS; PRP10; PRPF10; SAP155; SF3b155
Summary This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
Shipping Ambient
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA108316 SF3B1 CRISPRa kit - CRISPR gene activation of human splicing factor 3b subunit 1 1 kit
$1,657.00
KN219649 SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219649BN SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219649LP SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419649 SF3B1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products