Human SAP155 (SF3B1) activation kit by CRISPRa

SKU
GA108316
SF3B1 CRISPRa kit - CRISPR gene activation of human splicing factor 3b subunit 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SF3B1
Locus ID 23451
Components

GA108316G1, SAP155 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108316G2, SAP155 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108316G3, SAP155 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001005526, NM_001308824, NM_012433
UniProt ID O75533
Synonyms Hsh155; MDS; PRP10; PRPF10; SAP155; SF3b155
Summary This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN219649 SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN219649BN SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219649LP SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219649RB SF3B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419649 SF3B1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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