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BRG1 (SMARCA4) Human Gene Knockout Kit (CRISPR)

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SKU
KN219258LP
SMARCA4 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "BRG1 or NM_001128844"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol BRG1
Locus ID 6597
Components

KN219258G1, BRG1 gRNA vector 1 in pCas-Guide CRISPR vector

KN219258G2, BRG1 gRNA vector 2 in pCas-Guide CRISPR vector

KN219258LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001128844, NM_001128845, NM_001128846, NM_001128847, NM_001128848, NM_001128849, NM_003072
UniProt ID P51532
Synonyms BAF190; BAF190A; BRG1; CSS4; hSNF2b; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2
Summary The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2012
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Other Versions
SKU Description Size Price
GA104511 SMARCA4 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1 kit
$1,657.00
KN219258 SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219258BN SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219258RB SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419258 SMARCA4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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