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Human BRG1 (SMARCA4) activation kit by CRISPRa

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SKU
GA104511
SMARCA4 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC226420 SMARCA4 (Myc-DDK-tagged)-Human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 1
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Other products for "SMARCA4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SMARCA4
Locus ID 6597
Components

GA104511G1, BRG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104511G2, BRG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104511G3, BRG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001128844, NM_001128845, NM_001128846, NM_001128847, NM_001128848, NM_001128849, NM_003072
UniProt ID P51532
Synonyms BAF190; BAF190A; BRG1; CSS4; hSNF2b; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2
Summary The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN219258 SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219258BN SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219258LP SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219258RB SMARCA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419258 SMARCA4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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