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PTP kappa (PTPRK) Human Gene Knockout Kit (CRISPR)

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SKU
KN217570BN
PTPRK - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PTP kappa or NM_001135648"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PTP kappa
Locus ID 5796
Components

KN217570G1, PTP kappa gRNA vector 1 in pCas-Guide CRISPR vector

KN217570G2, PTP kappa gRNA vector 2 in pCas-Guide CRISPR vector

KN217570BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001135648, NM_001291981, NM_001291982, NM_001291983, NM_001291984, NM_002844
UniProt ID Q15262
Synonyms R-PTP-kappa
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA103940 PTPRK CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type K 1 kit
$1,657.00
KN217570 PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217570LP PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217570RB PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN417570 PTPRK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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