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Human PTP kappa (PTPRK) activation kit by CRISPRa

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SKU
GA103940
PTPRK CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type K
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC227943 PTPRK (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, K (PTPRK), transcript variant 1
10 ug
$1,855.00

Other products for "PTPRK"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPRK
Locus ID 5796
Components

GA103940G1, PTP kappa gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103940G2, PTP kappa gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103940G3, PTP kappa gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001135648, NM_001291981, NM_001291982, NM_001291983, NM_001291984, NM_002844
UniProt ID Q15262
Synonyms R-PTP-kappa
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN217570 PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217570BN PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217570LP PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217570RB PTPRK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN417570 PTPRK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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