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CD22 Human Gene Knockout Kit (CRISPR)

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SKU
KN216939BN
CD22 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CD22 or NM_001185099"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol CD22
Locus ID 933
Components

KN216939G1, CD22 gRNA vector 1 in pCas-Guide CRISPR vector

KN216939G2, CD22 gRNA vector 2 in pCas-Guide CRISPR vector

KN216939BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001185099, NM_001185100, NM_001185101, NM_001278417, NM_001771
UniProt ID P20273
Synonyms SIGLEC-2; SIGLEC2
Summary Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA100660 CD22 CRISPRa kit - CRISPR gene activation of human CD22 molecule 1 kit
$1,657.00
KN216939 CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216939LP CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216939RB CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416939 CD22 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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