OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human CD22 activation kit by CRISPRa

Be the first to review this product
SKU
GA100660
CD22 CRISPRa kit - CRISPR gene activation of human CD22 molecule
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA506407 CD22 mouse monoclonal antibody, clone OTI1F12 (formerly 1F12) 100 ul
$447.00
RC231365 CD22 (Myc-DDK-tagged)-Human CD22 molecule (CD22), transcript variant 4
10 ug
$589.00 $614.00

Other products for "CD22"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CD22
Locus ID 933
Components

GA100660G1, CD22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100660G2, CD22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100660G3, CD22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001185099, NM_001185100, NM_001185101, NM_001278417, NM_001771
UniProt ID P20273
Synonyms SIGLEC-2; SIGLEC2
Summary Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.UniProtKB/Swiss-Prot Function
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN216939 CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216939BN CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216939LP CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216939RB CD22 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416939 CD22 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products