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POLR2A Human Gene Knockout Kit (CRISPR)

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SKU
KN216765BN
POLR2A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "POLR2A or NM_000937"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol POLR2A
Locus ID 5430
Components

KN216765G1, POLR2A gRNA vector 1 in pCas-Guide CRISPR vector

KN216765G2, POLR2A gRNA vector 2 in pCas-Guide CRISPR vector

KN216765BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000937
UniProt ID P24928
Synonyms hRPB220; hsRPB1; POLR2; POLRA; RPB1; RPBh1; RpIILS; RPO2; RPOL2
Summary This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA103653 POLR2A CRISPRa kit - CRISPR gene activation of human RNA polymerase II subunit A 1 kit
$1,657.00
KN216765 POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216765LP POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216765RB POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416765 POLR2A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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