Human POLR2A activation kit by CRISPRa

SKU
GA103653
POLR2A CRISPRa kit - CRISPR gene activation of human RNA polymerase II subunit A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol POLR2A
Locus ID 5430
Components

GA103653G1, POLR2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103653G2, POLR2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103653G3, POLR2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000937
UniProt ID P24928
Synonyms hRPB220; hsRPB1; POLR2; POLRA; RPB1; RPBh1; RpIILS; RPO2; RPOL2
Summary This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. provided by RefSeq, Jul 2008
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Other Versions
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KN216765 POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN216765BN POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN216765LP POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN216765RB POLR2A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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