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CARD15 (NOD2) Human Gene Knockout Kit (CRISPR)

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SKU
KN215750RB
NOD2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CARD15 or NM_001293557"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol CARD15
Locus ID 64127
Components

KN215750G1, CARD15 gRNA vector 1 in pCas-Guide CRISPR vector

KN215750G2, CARD15 gRNA vector 2 in pCas-Guide CRISPR vector

KN215750RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001293557, NM_022162, NM_001370466, NR_163434
UniProt ID Q9HC29
Synonyms ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1
Summary This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jun 2014
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Documents
Resources
Other Versions
SKU Description Size Price
GA111990 NOD2 CRISPRa kit - CRISPR gene activation of human nucleotide binding oligomerization domain containing 2 1 kit
$1,657.00
KN215750 NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215750BN NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215750LP NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415750 NOD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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