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Human CARD15 (NOD2) activation kit by CRISPRa

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SKU
GA111990
NOD2 CRISPRa kit - CRISPR gene activation of human nucleotide binding oligomerization domain containing 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC215750 NOD2 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2)
10 ug
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Other products for "NOD2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NOD2
Locus ID 64127
Components

GA111990G1, CARD15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111990G2, CARD15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111990G3, CARD15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001293557, NM_022162, NM_001370466, NR_163434
UniProt ID Q9HC29
Synonyms ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1
Summary This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jun 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN215750 NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215750BN NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215750LP NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215750RB NOD2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415750 NOD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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