LMX1A Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | LMX1A |
| Locus ID | 4009 |
| Components |
KN215375G1, LMX1A gRNA vector 1 in pCas-Guide CRISPR vector KN215375G2, LMX1A gRNA vector 2 in pCas-Guide CRISPR vector KN215375BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001033507, NM_001174069, NM_177398, NM_177399 |
| UniProt ID | Q8TE12 |
| Synonyms | dr; dreher; LIM homeobox transcription factor 1 alpha; LMX-1; LMX1; LMX1.1; Lmx1.1; MGC87616; MGC129356; MGC129357; OTTMUSP00000022889; OTTMUSP00000022890; shaker short-tail; sst |
| Summary | This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. provided by RefSeq, Feb 2012 |
| Shipping | Ambient |
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA102717 | LMX1A CRISPRa kit - CRISPR gene activation of human LIM homeobox transcription factor 1 alpha | 1 kit |
$1,657.00
|
|
| KN215375 | LMX1A - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN215375LP | LMX1A - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN215375RB | LMX1A - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN415375 | LMX1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
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