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LMX1A Human Gene Knockout Kit (CRISPR)

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SKU
KN215375
LMX1A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "LMX1A or NM_001033507"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol LMX1A
Locus ID 4009
Components

KN215375G1, LMX1A gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: CCAAAGCGCGATCGACACCT

KN215375G2, LMX1A gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: AGTGTTCAGGCCGTGCGTCC

KN215375D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

CGCACCCCAA CAGAGCGCAG CGCCAGGAGT CCAGAAGCGG GCGGGACGCC CTCCGGGTCC CTTACAGTGC CCCTTCTCGA CCTGGGGCAG GTGAGGGCCG CAACGGGGCG GCTGGGACGC GGGATTGCAA ACCCCATCGT CCCGCGTGCC TGGACCCGGT CGCTCGAGGG AGGGTACCCA CTCTTTATAT ACCCAATATA CCCCAGTAGC TGCGTTCCTG CAGAGACGTC CCGAGGGCCC ACCTTCGTAT AGGTTGGGGC GGAGTCGGAT TCGGGATGGA AAACCTGGGG CAAGGGATGT AGGTGGGGGT GAGGGGGGCA GGAGAAGGAG AAACGCAGTT GGGGGGCGGA GGCCTAAGTA CATAACGTGT TGACTTCAAG TGAAATCAGA TCAGCCAGAG CAGTTCGCTG TGACTGATCT CTCCTCCCAC CCTACATTCT CTTGGCTGGA CCCTATCCTC CTGGCTGATT CTGGTCGCCC TGGACACTCC CTCAGTTCTT TCCCAGGAGT GCGGTGGCTG CTGGCGCCGA GTCCCAGCGG GCACGGACGT CAGACGCATC GTTTCTTCTC CTCTACAGGT CCTCCCGGCC CGGCCCGAAC TGGGCGCACT CTCTTTCCGC TTGGCGCTGA GCTCTGGAGC CCCGCTCTCT GGGACCTGGT CCGCGATAGG GAAGCTAGCG CCCCTCTTCA TACACTAAAT TGAGCCCCAT CACTATCTGT CCGTCAGTGC TTGTGGGTCG TCCCTACCCA AATAAATCCA ACAAGCCGCC CCAGGCCTCA CGCACTGGGC ACCGAATTCC CCAAAGCCGC GAGGGGCGGG CGAGCTTGTT CGTAGGCGTC TGAGTGGCAA GTGATTAAAA ATACCCAGGG CTGGATTTTT AATCTCGGAG CTGATCGACG TCTCATAAAT GCCGCCCTCT TCTCGCGGCC TAGAGGCAAT AGCATCCGAG ACCCGAGGCC TGGAGCGCCC AAGTTCGAGG AGGCTTCTCT CCCCCACCAA CTCCAGCCCC AATTTCAGCC ATGGGCAAGG CCGAGAGAGA CTTTTCTGGG CCAGTAGGCA ACGCAGCGCG GGGATTAGAC CGCGCGGCTG GGCCCTAGGC TCCGCGTTAA TTAACTGGAG CTGGATGTCG GGTCCTGTGG GTCCCCCCTC ACAACTCCTT TGCAGCGACA GAGGAGGAGC AGCGAGTCAA GGACCCCGGA

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001033507, NM_001174069, NM_177398, NM_177399
UniProt ID Q8TE12
Synonyms dr; dreher; LIM homeobox transcription factor 1 alpha; LMX-1; LMX1; LMX1.1; Lmx1.1; MGC87616; MGC129356; MGC129357; OTTMUSP00000022889; OTTMUSP00000022890; shaker short-tail; sst
Summary This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. provided by RefSeq, Feb 2012
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Documents
Resources
Other Versions
SKU Description Size Price
GA102717 LMX1A CRISPRa kit - CRISPR gene activation of human LIM homeobox transcription factor 1 alpha 1 kit
$1,657.00
KN215375BN LMX1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215375LP LMX1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215375RB LMX1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415375 LMX1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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